Endocrine Abstracts

Abstract: We report the case of a 65-year-old man who presented with erectile dysfunction to an appointment in our Endocrinology department. He referred fatigue, weight gain and constipation as secondary complaints that had been steadily evolving throughout the past 4 years. He denied other symptoms such as visual impairment or headaches as well as the consumption of any medications or drugs. His past medical history was unremarkable. On examination, BMI was 25.8 kg/m2</s...

Introduction: Ultrasound-guided fine-needle aspiration cytology (US-FNAC), the gold standard method to distinguish benign from malignant thyroid nodules, is the most accurate, cost-effective and minimal invasive preoperative test, aiming to resolve patient management. However, up to 30% of US-FNACs are classified as indeterminate nodules, making difficult to avoid unnecessary surgeries. Molecular tests may contribute to refine the preoperative diagnosis of thyroid nodules....

Introduction: The diagnostic gold standard for thyroid nodular disease is ultrasound-guided fine-needle aspiration cytology (US-FNAC), being the most accurate, cost-effective and minimal invasive preoperative test to distinguish benign from malignant nodules, aiming to resolve patient management. However, up to 30% of FNACs are classified as indeterminate nodules, turning difficult the decision on patient management to avoid unnecessary surgeries. The development of thyroid ca...

Introdution: Erdheim-Chester disease is a rare multisystemic form of Non-langerhans cell histiocytosis CD67 positive, with approximately 550 published cases. Papillary carcinoma is the most common thyroid cancer with BRAF V600E the most common mutation. Both diseases may be associated to BRAF V600E mutation. If Erdheim- Chester disease is positive to this mutation on histiocytes, a specific pharmacolgical treatment is available, (vemurafenib), with better results.<p class=...